220s BC

Anatolia

• Attalus I of Pergamon wins the Battle of the Harpasus in western Anatolia.

Illyria

• The First Illyrian War starts when the Roman Senate dispatches an army under the command of the consuls Lucius Postumius Albinus and Gnaeus Fulvius Centumalus to Illyria. Rome forces the withdrawal of Illyrian garrisons in the Greek cities of Epidamnus, Apollonia, Corcyra and Pharos and establishes a protectorate over these Greek towns.
• The Illyrian tribe of the Ardiaei is subdued by the Romans.
• The King of Macedonia, Demetrius II, dies. His nephew, Antigonus III comes to the Macedonian throne as regent for his half-cousin and the future king Philip V, who is only ten years old.
• Concerned at Rome's expansion, Antigonus III pursues a policy of befriending the Illyrians, even though the Greeks in the region support Rome in quelling the Illyrian pirates.
• The involvement of Rome in Illyria leads to the establishment of friendly relations between Rome and the enemies of Macedonia: the Aetolian League and Achaean League, which approve the suppression of Illyrian piracy.
• Aratus of Sicyon brings Argos into the Achaean League and then helps liberate Athens. This brings Aratus into conflict with Sparta.

China

• The state of Qin conquers the state of Zhao.

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