1,2-dihydroxynaphthalene dioxygenase

1,2-dihydroxynaphthalene dioxygenase
1,2-dihydroxynaphthalene dioxygenase oktamer, Pseudomonas
Identifiers
EC number 1.13.11.56
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

1,2-dihydroxynaphthalene dioxygenase (EC 1.13.11.56, 1,2-DHN dioxygenase, DHNDO, 1,2-dihydroxynaphthalene oxygenase, 1,2-dihydroxynaphthalene:oxygen oxidoreductase) is an enzyme with systematic name naphthalene-1,2-diol:oxygen oxidoreductase.[1][2][3] This enzyme catalyses the following chemical reaction

naphthalene-1,2-diol + O2 2-hydroxy-2H-chromene-2-carboxylate

This enzyme is involved in naphthalene degradation.

References

  1. Kuhm, A.E.; Stolz, A.; Ngai, K.L.; Knackmuss, H.J. (1991). "Purification and characterization of a 1,2-dihydroxynaphthalene dioxygenase from a bacterium that degrades naphthalenesulfonic acids". J. Bacteriol. 173 (12): 3795–3802. PMC 208010. PMID 2050635.
  2. Keck, A.; Conradt, D.; Mahler, A.; Stolz, A.; Mattes, R.; Klein, J. (2006). "Identification and functional analysis of the genes for naphthalenesulfonate catabolism by Sphingomonas xenophaga BN6". Microbiology. 152 (Pt 7): 1929–1940. doi:10.1099/mic.0.28783-0. PMID 16804169.
  3. Patel, T.R.; Barnsley, E.A. (1980). "Naphthalene metabolism by pseudomonads: purification and properties of 1,2-dihydroxynaphthalene oxygenase". J. Bacteriol. 143 (2): 668–673. PMC 294337. PMID 7204331.
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