Tetrose

A tetrose is a monosaccharide with 4 carbon atoms. They have either an aldehyde functional group in position 1 (aldotetroses) or a ketone functional group in position 2 (ketotetroses).[1][2]

  • D-Erythrose
  • D-Threose
  • D-Erythrulose

The aldotetroses have two chiral centers (asymmetric carbon atoms) and so 4 different stereoisomers are possible. There are two naturally occurring stereoisomers, the enantiomers of erythrose and threose having the D configuration but not the L enantiomers. The ketotetroses have one chiral center and, therefore, two possible stereoisomers: erythrulose (L- and D-form). Again, only the D enantiomer is naturally occurring.

References
  1. Lindhorst TK (2007). Essentials of Carbohydrate Chemistry and Biochemistry (1st ed.). Wiley-VCH. ISBN 978-3-527-31528-4.
  2. Robyt JF (1997). Essentials of Carbohydrate Chemistry (1 ed.). Springer. ISBN 0-387-94951-8.
  3. Batt RD, Dickens F, Williamson DH (November 1960). "Tetrose metabolism. 2. The utilization of tetroses and tetritols by rat tissues". The Biochemical Journal. 77 (2): 281–94. doi:10.1042/bj0770281. PMC 1204983. PMID 13687765.
  4. Garrett RH, Grisham CM (2017). Biochemistry. Boston, MA: Cengage Learning. pp. 755–794. ISBN 978-1-305-57720-6.
  5. Horecker BL, Smyrniotis PZ, Hiatt HH, Marks PA (February 1955). "Tetrose phosphate and the formation of sedoheptulose diphosphate". The Journal of Biological Chemistry. 212 (2): 827–36. PMID 14353884.
  6. Garrett RH, Grisham CM (2017). Biochemistry. Boston, MA: Cengage Learning. pp. 611–642. ISBN 978-1-305-57720-6.
  7. Racker E, Klybas V, Schramm M (October 1959). "Tetrose diphosphate, a specific inhibitor of glyceraldehyde 3-phosphate dehydrogenase". The Journal of Biological Chemistry. 234: 2510–6. PMID 14435686.
  8. Grazi E, De Flora A, Pontremoli S (February 1960). "The inhibition of phosphoglucose isomerase by D-erythrose 4-phosphate". Biochemical and Biophysical Research Communications. 2 (2): 121–5. doi:10.1016/0006-291X(60)90201-1.


This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.