Sulfoacetaldehyde dehydrogenase (acylating)
Sulfoacetaldehyde dehydrogenase (acylating) (EC 1.2.1.81, SauS) is an enzyme with systematic name 2-sulfoacetaldehyde:NADP+ oxidoreductase (CoA-acetylating).[1] This enzyme catalyses the following chemical reaction
- 2-sulfoacetaldehyde + CoA + NADP+ sulfoacetyl-CoA + NADPH + H+
| Sulfoacetaldehyde dehydrogenase (acylating) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 1.2.1.81 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
The enzyme is involved in degradation of sulfoacetate.
References
- Weinitschke S, Hollemeyer K, Kusian B, Bowien B, Smits TH, Cook AM (November 2010). "Sulfoacetate is degraded via a novel pathway involving sulfoacetyl-CoA and sulfoacetaldehyde in Cupriavidus necator H16". The Journal of Biological Chemistry. 285 (46): 35249–54. doi:10.1074/jbc.M110.127043. PMC 2975148. PMID 20693281.
External links
- Sulfoacetaldehyde+dehydrogenase+(acylating) at the US National Library of Medicine Medical Subject Headings (MeSH)
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