Succinate—citramalate CoA-transferase

In enzymology, a succinate-citramalate CoA-transferase (EC 2.8.3.7) is an enzyme that catalyzes the chemical reaction

succinyl-CoA + citramalate succinate + citramalyl-CoA
succinate-citramalate CoA-transferase
Identifiers
EC number2.8.3.7
CAS number9033-60-7
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

Thus, the two substrates of this enzyme are succinyl-CoA and citramalate, whereas its two products are succinate and citramalyl-CoA.

This enzyme belongs to the family of transferases, specifically the CoA-transferases. The systematic name of this enzyme class is succinyl-CoA:citramalate CoA-transferase. Other names in common use include itaconate CoA-transferase, citramalate CoA-transferase, citramalate coenzyme A-transferase, and succinyl coenzyme A-citramalyl coenzyme A transferase. This enzyme participates in c5-branched dibasic acid metabolism.

References

    • Cooper RA, Kornberg HL (1964). "The utilization of itaconate by Pseudomonas sp". Biochem. J. 91 (1): 82–91. PMC 1202819. PMID 4284209.


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