Streptogrisin A
Streptogrisin A (EC 3.4.21.80, Streptomyces griseus protease A, protease A, proteinase A, Streptomyces griseus proteinase A, Streptomyces griseus serine proteinase 3, Streptomyces griseus serine proteinase A) is an enzyme.[1][2][3][4][5] This enzyme catalyses the following chemical reaction
- Hydrolysis of proteins with specificity similar to chymotrypsin
| Streptogrisin A | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 3.4.21.80 | ||||||||
| CAS number | 55326-50-6 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
This enzyme is isolated from Streptomyces griseus.
References
- Johnson P, Smillie LB (May 1971). "The disulfide bridge sequences of a serine protease of wide specificity from Streptomyces griseus". Canadian Journal of Biochemistry. 49 (5): 548–62. doi:10.1139/o71-082. PMID 5575653.
- Sielecki AR, Hendrickson WA, Broughton CG, Delbaere LT, Brayer GD, James MN (November 1979). "Protein structure refinement: Streptomyces griseus serine protease A at 1.8 A resolution". Journal of Molecular Biology. 134 (4): 781–804. doi:10.1016/0022-2836(79)90486-8. PMID 119870.
- James MN, Sielecki AR, Brayer GD, Delbaere LT, Bauer CA (November 1980). "Structures of product and inhibitor complexes of Streptomyces griseus protease A at 1.8 A resolution. A model for serine protease catalysis". Journal of Molecular Biology. 144 (1): 43–88. doi:10.1016/0022-2836(80)90214-4. PMID 6783761.
- Delbaere LT, Brayer GD (May 1985). "The 1.8 A structure of the complex between chymostatin and Streptomyces griseus protease A. A model for serine protease catalytic tetrahedral intermediates". Journal of Molecular Biology. 183 (1): 89–103. doi:10.1016/0022-2836(85)90283-9. PMID 3892018.
- Henderson G, Krygsman P, Liu CJ, Davey CC, Malek LT (August 1987). "Characterization and structure of genes for proteases A and B from Streptomyces griseus". Journal of Bacteriology. 169 (8): 3778–84. PMC 212465. PMID 3112129.
External links
- Streptogrisin+A at the US National Library of Medicine Medical Subject Headings (MeSH)
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