Sortase B

Sortase B (EC 3.4.22.71, SrtB) is an enzyme.[1][2] This enzyme catalyses the following chemical reaction

The enzyme catalyses a cell wall sorting reaction in which a surface protein with a sorting signal containing a NXTN motif is cleaved.
Sortase B
Identifiers
EC number3.4.22.71
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

This enzyme belongs to the peptidase family C60.

References

  1. Zong Y, Mazmanian SK, Schneewind O, Narayana SV (January 2004). "The structure of sortase B, a cysteine transpeptidase that tethers surface protein to the Staphylococcus aureus cell wall". Structure. 12 (1): 105–12. doi:10.1016/j.str.2003.11.021. PMID 14725770.
  2. Bierne H, Garandeau C, Pucciarelli MG, Sabet C, Newton S, Garcia-del Portillo F, Cossart P, Charbit A (April 2004). "Sortase B, a new class of sortase in Listeria monocytogenes". Journal of Bacteriology. 186 (7): 1972–82. doi:10.1128/jb.186.7.1972-1982.2004. PMC 374393. PMID 15028680.
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