Sermorelin

Sermorelin acetate (INN; brand names Geref, Gerel), also known as GHRH (1-29), is a peptide analogue of growth hormone-releasing hormone (GHRH) which is used as a diagnostic agent to assess growth hormone (GH) secretion for the purpose of diagnosing growth hormone deficiency. It is a 29-amino acid polypeptide representing the 1–29 fragment from endogenous human GHRH, thought to be the shortest fully functional fragment of GHRH.[1][2]

Sermorelin
Clinical data
Trade namesGeref, Gerel
Other namesGRF 1–29
AHFS/Drugs.comMicromedex Detailed Consumer Information
Pregnancy
category
  • US: C (Risk not ruled out)
    Routes of
    administration
    Injection
    ATC code
    Legal status
    Legal status
    • US: Discontinued
    Identifiers
    CAS Number
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    ChemSpider
    UNII
    KEGG
    ChEMBL
    CompTox Dashboard (EPA)
    Chemical and physical data
    FormulaC149H246N44O42S
    Molar mass3357.93 g·mol−1
    3D model (JSmol)
     NY (what is this?)  (verify)

    See also

    References

    1. Prakash A, Goa KL (August 1999). "Sermorelin: a review of its use in the diagnosis and treatment of children with idiopathic growth hormone deficiency". BioDrugs. 12 (2): 139–57. doi:10.2165/00063030-199912020-00007. PMID 18031173.
    2. Pharmacology (Rang, Dale, Ritter & Moore, ISBN 0-443-07145-4, 5th ed., Churchill Livingstone 2003).



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