Pseudooxynicotine oxidase

Pseudooxynicotine oxidase (EC 1.4.3.24) is an enzyme with systematic name 4-(methylamino)-1-(pyridin-3-yl)butan-1-one:oxygen oxidoreductase (methylamine releasing).[1] This enzyme catalyses the following chemical reaction

4-(methylamino)-1-(pyridin-3-yl)butan-1-one + H2O + O2 4-oxo-4-(pyridin-3-yl)butanal + methylamine + H2O2
Pseudooxynicotine oxidase
Identifiers
EC number1.4.3.24
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

This enzyme contains one non-covalently bound FAD.

References

  1. Qiu J, Ma Y, Wen Y, Chen L, Wu L, Liu W (April 2012). "Functional identification of two novel genes from Pseudomonas sp. strain HZN6 involved in the catabolism of nicotine". Applied and Environmental Microbiology. 78 (7): 2154–60. doi:10.1128/AEM.07025-11. PMC 3302611. PMID 22267672.
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