Pregna-4,20-dien-3,6-dione

Pregnadienedione (PDD), or pregna-4,20-dien-3,6-dione, is a steroid and pherine, or synthetic pheromone.[1][2] PDD has been found to activate the vomeronasal organ in men.[1][2] Moreover, inhalation by men has been found to affect autonomic and central function and to lower luteinizing hormone and testosterone levels, while inhalation by women has few or no effects.[1][2]

Pregna-4,20-dien-3,6-dione
Clinical data
Other namesPregna-4,20-diene-3,6-dione
ATC code
  • None
Identifiers
PubChem CID
ChemSpider
Chemical and physical data
FormulaC21H28O2
Molar mass312.453 g·mol−1
3D model (JSmol)

See also

References

  1. Hayes W (2003). "Human pheromones: have they been demonstrated?". Behavioral Ecology and Sociobiology. 54 (2): 89–97. doi:10.1007/s00265-003-0613-4.
  2. Monti-Bloch, Louis; Diaz-Sanchez, Vicente; Jennings-White, Clive; Berliner, David L (1998). "Modulation of serum testosterone and autonomic function through stimulation of the male human vomeronasal organ (VNO) with pregna-4,20-diene-3,6-dione". The Journal of Steroid Biochemistry and Molecular Biology. 65 (1–6): 237–242. doi:10.1016/S0960-0760(98)00025-9. ISSN 0960-0760. PMID 9699878.


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