Polysaccharide O-methyltransferase
In enzymology, a polysaccharide O-methyltransferase (EC 2.1.1.18) is an enzyme that catalyzes the chemical reaction
- S-adenosyl-L-methionine + 1,4-alpha-D-glucooligosaccharide S-adenosyl-L-homocysteine + oligosaccharide containing 6-methyl-D-glucose units
| polysaccharide O-methyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.1.1.18 | ||||||||
| CAS number | 37205-56-4 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Thus, the two substrates of this enzyme are S-adenosyl methionine and 1,4-alpha-D-glucooligosaccharide, whereas its two products are S-adenosylhomocysteine and oligosaccharide containing 6-methyl-D-glucose units. This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:1,4-alpha-D-glucan 6-O-methyltransferase. Other names in common use include polysaccharide methyltransferase, and acylpolysacharide 6-methyltransferase.
References
- Ferguson JA, Ballou CE (1970). "Biosynthesis of a mycobacterial lipopolysaccharide. Properties of the polysaccharide methyltransferase". J. Biol. Chem. 245 (16): 4213–23. PMID 5503262.
Gene ontology (GO) codes
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