Polypyrimidine tract-binding protein
Polypyrimidine tract-binding protein, also known as PTB or hnRNP I, is an RNA-binding protein. PTB functions mainly as a splicing regulator, although it is also involved in alternative 3' end processing, mRNA stability and RNA localization.[1]
| polypyrimidine tract binding protein 1 | |
|---|---|
| Identifiers | |
| Symbol | PTBP1 |
| Alt. symbols | PTB |
| NCBI gene | 5725 |
| HGNC | 9583 |
| OMIM | 600693 |
| RefSeq | NM_002819 |
| UniProt | P26599 |
| Other data | |
| Locus | Chr. 19 p13.3 |
| polypyrimidine tract binding protein 2 | |
|---|---|
| Identifiers | |
| Symbol | PTBP2 |
| NCBI gene | 58155 |
| HGNC | 17662 |
| OMIM | 608449 |
| RefSeq | NM_021190 |
| UniProt | Q9UKA9 |
| Other data | |
| Locus | Chr. 1 p21.3-22.1 |
See also
References
- Valcárcel J, Gebauer F (November 1997). "Post-transcriptional regulation: the dawn of PTB". Curr. Biol. 7 (11): R705–8. doi:10.1016/S0960-9822(06)00361-7. PMID 9382788.
External links
- polypyrimidine+tract-binding+protein at the US National Library of Medicine Medical Subject Headings (MeSH)
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.