Nitrate reductase (NADPH)

Nitrate reductase (NADPH) (EC 1.7.1.3, assimilatory nitrate reductase, assimilatory reduced nicotinamide adenine dinucleotide phosphate-nitrate reductase, NADPH-nitrate reductase, assimilatory NADPH-nitrate reductase, triphosphopyridine nucleotide-nitrate reductase, NADPH:nitrate reductase, nitrate reductase (NADPH2), NADPH2:nitrate oxidoreductase) is an enzyme with systematic name nitrite:NADP+ oxidoreductase.[1][2][3][4] This enzyme catalises the following chemical reaction

nitrite + NADP+ + H2O nitrate + NADPH + H+
Nitrate reductase (NADPH)
Identifiers
EC number1.7.1.3
CAS number9029-28-1
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

Nitrate reductase is an iron-sulfur molybdenum flavoprotein.

References
  1. Nason A (1963). "Nitrate reductases". In Boyer PD, Lardy H, Myrbäck K (eds.). The Enzymes. 7 (2nd ed.). New York: Academic Press. pp. 587–607.
  2. Nason A, Evans HJ (June 1953). "Triphosphopyridine nucleotide-nitrate reductase in Neurospora". The Journal of Biological Chemistry. 202 (2): 655–73. PMID 13061490.
  3. Nicholas DJ, Nason A (March 1954). "Molybdenum and nitrate reductase. II. Molybdenum as a constituent of nitrate reductase". The Journal of Biological Chemistry. 207 (1): 353–60. PMID 13152110.
  4. Berks BC, Ferguson SJ, Moir JW, Richardson DJ (December 1995). "Enzymes and associated electron transport systems that catalyse the respiratory reduction of nitrogen oxides and oxyanions". Biochimica et Biophysica Acta (BBA) - Bioenergetics. 1232 (3): 97–173. doi:10.1016/0005-2728(95)00092-5. PMID 8534676.
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