NADH:ubiquinone reductase (non-electrogenic)
NADH:ubiquinone reductase (non-electrogenic) (EC 1.6.5.9, NDH-2, ubiquinone reductase, coenzyme Q reductase, dihydronicotinamide adenine dinucleotide-coenzyme Q reductase, DPNH-coenzyme Q reductase, DPNH-ubiquinone reductase, NADH-coenzyme Q oxidoreductase, NADH-coenzyme Q reductase, NADH-CoQ oxidoreductase, NADH-CoQ reductase) is an enzyme with systematic name NADH:ubiquinone oxidoreductase.[1][2][3][4] This enzyme catalyses the following chemical reaction
- NADH + H+ + ubiquinone NAD+ + ubiquinol
| NADH:ubiquinone reductase (non-electrogenic) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 1.6.5.9 | ||||||||
| CAS number | 9028-04-0 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
This enzyme is a flavoprotein (FAD).
References
- Moller, I.M; Palmer, J.M. (1982). "Direct evidence for the presence of a rotenone-resistant NADH dehydrogenase on the inner surface of plant mitochondria". Physiologia Plantarum. 54: 267–274. doi:10.1111/j.1399-3054.1982.tb00258.x.
- de Vries S, Grivell LA (September 1988). "Purification and characterization of a rotenone-insensitive NADH:Q6 oxidoreductase from mitochondria of Saccharomyces cerevisiae". European Journal of Biochemistry. 176 (2): 377–84. doi:10.1111/j.1432-1033.1988.tb14292.x. PMID 3138118.
- Kerscher SJ, Okun JG, Brandt U (July 1999). "A single external enzyme confers alternative NADH:ubiquinone oxidoreductase activity in Yarrowia lipolytica". Journal of Cell Science. 112 ( Pt 14) (14): 2347–54. PMID 10381390.
- Rasmusson AG, Soole KL, Elthon TE (2004). "Alternative NAD(P)H dehydrogenases of plant mitochondria". Annual Review of Plant Biology. 55: 23–39. doi:10.1146/annurev.arplant.55.031903.141720. PMID 15725055.
External links
- NADH:ubiquinone+reductase+(non-electrogenic) at the US National Library of Medicine Medical Subject Headings (MeSH)
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