Momordicin I
Momordicin I, or 3,7,23-trihydroxycucurbitan-5,24-dien-19-al, is a chemical compound found in the leaves of the bitter melon vine (Momordica charantia), possibly responsible for its reputed medicinal properties.
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| Names | |
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| IUPAC name
3,7-dihydroxy-17-(4-hydroxy-6-methylhept-5-en-2-yl)-4,4,13,14-tetramethyl-2,3,7,8,10,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthrene-9-carbaldehyde | |
| Other names
3,7,23-trihydroxycucurbitan-5,24-dien-19-al | |
| Identifiers | |
3D model (JSmol) |
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| ChemSpider | |
PubChem CID |
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| Properties | |
| C30H48O4 | |
| Molar mass | 472.710 g·mol−1 |
| Melting point | 125–128 °C (257–262 °F; 398–401 K) |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
| Infobox references | |
The compound was isolated and characterized in 1984 by M. Yasuda and others [1] It is a white crystalline solid with formula C
30H
48O
4, that melts at 125–128 °C.[2]
The compound can be extracted from ground dry leaves by dichloromethane. It is insoluble in water and soluble in methanol.[2]
A related glycoside, momordicoside, occurs in the unripe fruit.[2][3]
References
- M. Yasuda, M. Iwamoto, H. Okabe, and T. Yamauchi (1984), A New Cucurbitane Triterpenoid From Momordica charantia, Chem. Pharm. Bull. volume 32, issue 6, pages 2044-2049
- N. M. Puspawati (2008), Isolation and Identification of Momordicin I from leaves extract of Momordica charantia L. Archived 2011-07-21 at the Wayback Machine. Jurnal Kimia, volume 2, issue 1, pages 53-56
- H. Okabe, Y. Miyahara, and T. Yamauci (1982), Studies on the Constituents of Momordica charantia L. Chem. Pharm. Bull., volume 30, issue 12, pages 4334-4340
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