Mohammad Zahid Ashraf

Jamia Millia Islamia

Deep vein thrombosis of the right leg

Mohammad Zahid Ashraf, born in 1973,[1] graduated in biosciences from Jamia Millia Islamia in 1994 and continued there to secure a master's degree in 1996.[2] Subsequently, he did his doctoral research at Vallabhbhai Patel Chest Institute which earned him a PhD from the University of Delhi in 2001. His post-doctoral training was at the Lerner Research Institute of Cleveland Clinic and on his return to India, he joined the Defence Institute of Physiology and Allied Sciences (DIPAS) in 2009 as a scientist at grade D at its Genomics division which he headed from 2014 till 2017. He moved to his alma mater, Jamia Millia Islamia that year where he holds the position of a professor at the department of biotechnology.[3]

Ashraf leads a team of researchers who are involved in studies in the fields of Cardiovascular biology, Functional genomics, Molecular medicine and Translational biology.[4] He worked among the Indian army soldiers stationed in Siachen Glacier to study the effect of high altitude on venous thrombosis and his studies were published in the Proceedings of the National Academy of Sciences of the United States of America.[5] It was during these studies, he discovered the role played by novel regulator “Calpain” in pathogenesis of thrombosis.[6] He has published a number of articles;[7][note 1] ResearchGate, an online repository of scientific articles has listed 34 of them.[8]

Ashraf resides in Delhi, along the Mall Road.[1]

Ashraf was elected as a member of the National Academy of Medical Sciences in 2015.[9] and the National Academy of Sciences, India and the Indian Academy of Sciences elected him as a fellow in 2018.[1] The Department of Biotechnology of the Government of India awarded him the National Bioscience Award for Career Development, one of the highest Indian science awards, for him contributions to biosciences, in 2017–18.[10] He is also an invited member of the Pulmonary Vascular Research Institute[11] and a recipient of Innovations Award (2008) of the Cleveland Clinic Foundation, P.A. Kurup Oration Award (2014) of the Indian Society for Atherosclerosis Research and the Rear Admiral M. S. Malhotra Award (2014) of the Defence Research and Development Organisation.[12]

• Ashraf, Mohammad Z. (2015-12-10). "Hypertension at high altitude: the interplay between genetic and biochemical factors in the setting of oxidative stress". Hypertension Research. 39 (4): 199–200. doi:10.1038/hr.2015.140. PMID 26657006.
• Ashraf, Mohammad Z.; Singh, Shashi Bala; Ganju, Lilly; Sengupta, Shantanu; Bajaj, Nitin; Chatterjee, Tathagat; Nair, Velu; Ahmad, Yasmin; Sahu, Anita (2014-02-20). "Altered expression of platelet proteins and calpain activity mediate hypoxia-induced prothrombotic phenotype". Blood. 123 (8): 1250–1260. doi:10.1182/blood-2013-05-501924. ISSN 1528-0020. PMID 24297866.
• Podrez, Eugene A.; Sayre, Lawrence M.; Lin, De; Kar, Niladri S.; Ashraf, Mohammad Z.; Gao, Detao (2010-02-12). "Structural Basis for the Recognition of Oxidized Phospholipids in Oxidized Low Density Lipoproteins by Class B Scavenger Receptors CD36 and SR-BI". Journal of Biological Chemistry. 285 (7): 4447–4454. doi:10.1074/jbc.M109.082800. ISSN 1083-351X. PMC 2836050. PMID 19996318.
• Podrez, Eugene A.; Valiyaveettil, Manojkumar; Ashraf, Mohammad Z.; Kar, Niladri S. (2008-03-28). "Mapping and Characterization of the Binding Site for Specific Oxidized Phospholipids and Oxidized Low Density Lipoprotein of Scavenger Receptor CD36". Journal of Biological Chemistry. 283 (13): 8765–8771. doi:10.1074/jbc.M709195200. ISSN 1083-351X. PMC 2417175. PMID 18245080.
• Podrez, Eugene A.; Febbraio, Maria; Byzova, Tatiana V.; Ashraf, Mohammad Z.; Kar, Niladri; Valiyaveettil, Manojkumar (2008-02-15). "Oxidized high-density lipoprotein inhibits platelet activation and aggregation via scavenger receptor BI". Blood. 111 (4): 1962–1971. doi:10.1182/blood-2007-08-107813. ISSN 1528-0020. PMC 2234045. PMID 17993610.