Methanesulfonate monooxygenase

Methanesulfonate monooxygenase (EC 1.14.13.111, mesylate monooxygenase, mesylate,reduced-FMN:oxygen oxidoreductase, MsmABCD, methanesulfonic acid monooxygenase, MSA monooxygenase, MSAMO) is an enzyme with systematic name methanesulfonate,NADH:oxygen oxidoreductase.[1][2] This enzyme catalyses the following chemical reaction

methanesulfonate + NADH + H+ + O2 formaldehyde + NAD+ + sulfite + H2O
Methanesulfonate monooxygenase
Identifiers
EC number1.14.13.111
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

Methanesulfonate monooxygenase is a flavoprotein.

References

  1. de Marco P, Moradas-Ferreira P, Higgins TP, McDonald I, Kenna EM, Murrell JC (April 1999). "Molecular analysis of a novel methanesulfonic acid monooxygenase from the methylotroph Methylosulfonomonas methylovora". Journal of Bacteriology. 181 (7): 2244–51. PMC 93639. PMID 10094704.
  2. Higgins TP, Davey M, Trickett J, Kelly DP, Murrell JC (February 1996). "Metabolism of methanesulfonic acid involves a multicomponent monooxygenase enzyme". Microbiology. 142 ( Pt 2): 251–60. doi:10.1099/13500872-142-2-251. PMID 8932698.
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