Malonyl-S-ACP:biotin-protein carboxyltransferase
Malonyl-S-ACP:biotin-protein carboxyltransferase (EC 2.1.3.10, malonyl-S-acyl-carrier protein:biotin-protein carboxyltransferase, MadC/MadD, MadC,D, malonyl-[acyl-carrier protein]:biotinyl-[protein] carboxyltransferase) is an enzyme with systematic name malonyl-(acyl-carrier protein):biotinyl-(protein) carboxytransferase.[1][2][3] This enzyme catalyses the following chemical reaction
- malonyl-[acyl-carrier protein] + biotinyl-[protein] acetyl-[acyl-carrier protein] + carboxybiotinyl-[protein]
| Malonyl-S-ACP:biotin-protein carboxyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.1.3.10 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
This enzyme is a component of EC 4.1.1.89, biotin-dependent malonate decarboxylase.
References
- Berg M, Hilbi H, Dimroth P (April 1997). "Sequence of a gene cluster from Malonomonas rubra encoding components of the malonate decarboxylase Na+ pump and evidence for their function". European Journal of Biochemistry. 245 (1): 103–15. doi:10.1111/j.1432-1033.1997.00103.x. PMID 9128730.
- Micklefield J, Harris KJ, Gröger S, Mocek U, Hilbi H, Dimroth P, Floss HG (1995). "Stereochemical course of malonate decarboxylase in Malonomonas rubra has biotin decarboxylation with retention". J. Am. Chem. Soc. 117: 1153–1154. doi:10.1021/ja00108a042.
- Dimroth P, Hilbi H (July 1997). "Enzymic and genetic basis for bacterial growth on malonate". Molecular Microbiology. 25 (1): 3–10. doi:10.1046/j.1365-2958.1997.4611824.x. PMID 11902724.
External links
- Malonyl-S-ACP:biotin-protein+carboxyltransferase at the US National Library of Medicine Medical Subject Headings (MeSH)
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