Liquiritin
Liquiritin is the 4'-O-glucoside of the flavanone liquiritigenin. Liquiritin is one of flavone compounds derived from licorice[1].
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| Other names
Liquiritoside Liquiritigenin-4'-O-glucoside | |
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| Properties | |
| C21H22O9 | |
| Molar mass | 418.398 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
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De novo biosynthesis of liquiritin in Saccharomyces cerevisiae using endogenous yeast metabolites as precursors and cofactors, provides a possibility for the economical and sustainable production and application of licorice flavonoids through synthetic biology[2].
References
- Cong, J. X., Wang, S. Y., Wu, X. H., & Yu, P. (2012). Optimization of Separation Conditions of Liquiritin in Preparative Liquid Chromatography. In Advanced Materials Research (Vol. 550, pp. 1647-1652). Trans Tech Publications Ltd.
- Yin, Y., Li, Y., Jiang, D., Zhang, X., Gao, W., & Liu, C. (2019). De novo biosynthesis of liquiritin in Saccharomyces cerevisiae. Acta Pharmaceutica Sinica B. 10(4): 711–721 doi:10.1016/j.apsb.2019.07.005 PMC 7161706 PMID 32322472
Further reading
- Wang, J.; Wang, D.; Yu, J.; Liu, C.; Li, L.; Zhang, Y. (2013). "Isolation of Liquiritigenin-4'-Apiosyl-Glucoside and Liquiritin from the Root of Glycyrrhiza uralensis by High-Performance Centrifugal Partition Chromatography". Journal of Chromatographic Science. 52 (4): 310–314. doi:10.1093/chromsci/bmt029. ISSN 0021-9665. PMID 23552847.
- Cong, Jing Xiang; Wang, Shao Yan; Gao, Hong (2012). "Separation of Liquiritin by Two-Dimensional Liquid Chromatography". Advanced Materials Research. 455-456: 1232–1238. doi:10.4028/www.scientific.net/AMR.455-456.1232. ISSN 1662-8985.
- Cong, Jingxiang; Lin, Bingchang (2007). "Separation of Liquiritin by simulated moving bed chromatography". Journal of Chromatography A. 1145 (1–2): 190–194. doi:10.1016/j.chroma.2007.01.088. ISSN 0021-9673. PMID 17289063.
- Ni, H., Xu, M., Xie, K., Fei, Y., Deng, H., He, Q., ... & Yao, M. (2020). "Liquiritin alleviates pain through inhibiting CXCL1/CXCR2 signaling pathway in bone cancer pain rat". Frontiers in Pharmacology, 11. doi:10.3389/fphar.2020.00436 PMC 7193085 PMID 32390832
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