LY-2452473

LY-2452473 (TT-701) is a drug which acts as a selective androgen receptor modulator (SARM). It has been investigated for the treatment of erectile dysfunction and symptoms associated with benign prostate hyperplasia.[1][2]

LY-2452473
Legal status
Legal status
  • US: Investigational drug
Identifiers
CAS Number
PubChem CID
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC22H22N4O2
Molar mass374.4 g·mol−1
3D model (JSmol)

See also

References

  1. Yi P, Rehmel JF, Cassidy K, Hadden C, Campanale K, Patel N, Johnson J (December 2012). "Disposition and metabolism of LY2452473, a selective androgen receptor modulator, in humans". Drug Metabolism and Disposition: The Biological Fate of Chemicals. 40 (12): 2354–64. doi:10.1124/dmd.112.047613. PMID 22961682.
  2. Noey EL, Yang Z, Li Y, Yu H, Richey RN, Merritt JM, Kjell DP, Houk KN (June 2017). "Origins of Regioselectivity in the Fischer Indole Synthesis of a Selective Androgen Receptor Modulator". The Journal of Organic Chemistry. 82 (11): 5904–5909. doi:10.1021/acs.joc.7b00878. PMID 28467062.
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