Iscotrizinol

Iscotrizinol (USAN,[1] INCI diethylhexyl butamido triazone) is an organic compound used in sunscreens to absorb UVB and some UVA radiation [2] with a peak protection at 310nm.[3] It is one of the most photostable chemical sunscreens known today with 25 hours required to lose 10% of its SPF protection ability.[4] It is marketed as Uvasorb HEB by 3V Sigma.

Iscotrizinol
Names
IUPAC name
4,4'-[[6-[[4-[[(1,1-dimethylethyl)amino]carbonyl]phenyl]amino]-1,3,5-triazine-2,4-diyl]diimino]bis-, bis(2-ethylhexyl)benzoate
Other names
Diethylhexyl butamido triazone (INCI),
Uvasorb HEB (trade name)
Identifiers
3D model (JSmol)
ChemSpider
ECHA InfoCard 100.102.002
KEGG
UNII
Properties
C44H59N7O5
Molar mass 765.981
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

References

  1. Statement on a nonproprietary name adopted by the USAN Council
  2. incidecoder.com: Diethylhexyl Butamido Triazone
  3. Couteau C, Pommier M, Paparis E, Coiffard LJ (June 2007). "Study of the efficacy of 18 sun filters authorized in European Union tested in vitro". Pharmazie. 62: 449–452. doi:10.1691/ph.2007.6.6247. PMID 17663193.
  4. Couteau C, Faure A, Fortin J, Paparis E, Coiffard LJ (May 2007). "Study of the photostability of 18 sunscreens in creams by measuring the SPF in vitro". Journal of Pharmaceutical and Biomedical Analysis. 44: 270–273. doi:10.1016/j.jpba.2007.01.052.


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