Hydroxymalonate dehydrogenase

In enzymology, a hydroxymalonate dehydrogenase (EC 1.1.1.167) is an enzyme that catalyzes the chemical reaction

hydroxymalonate + NAD+ oxomalonate + NADH + H+
hydroxymalonate dehydrogenase
Identifiers
EC number1.1.1.167
CAS number58693-60-0
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

Thus, the two substrates of this enzyme are hydroxymalonate and NAD+, whereas its 3 products are oxomalonate, NADH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is hydroxymalonate:NAD+ oxidoreductase.

References

    • Jukova NI, Klunova SM, Philippovich YB (1971). Biochemistry of Insects. Moscow: V.I. Lenin State Pedagogical Institute (17): 56. Missing or empty |title= (help)


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