Glycoprotein N-palmitoyltransferase
In enzymology, a glycoprotein N-palmitoyltransferase (EC 2.3.1.96) is an enzyme that catalyzes the chemical reaction
- palmitoyl-CoA + glycoprotein CoA + N-palmitoylglycoprotein
| glycoprotein N-palmitoyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.3.1.96 | ||||||||
| CAS number | 97162-74-8 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Thus, the two substrates of this enzyme are palmitoyl-CoA and glycoprotein, whereas its two products are CoA and N-palmitoylglycoprotein.
This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is palmitoyl-CoA:glycoprotein N-palmitoyltransferase. This enzyme is also called mucus glycoprotein fatty acyltransferase. This enzyme participates in aminosugars metabolism. This enzyme has at least one effector, Dithiothreitol.
References
- Liau YH, Slomiany BL, Slomiany A, Piasek A, Palmer D, Rosenthal WS (1985). "Identification of mucus glycoprotein fatty acyltransferase activity in human gastric mucosa". Digestion. 32 (1): 57–62. doi:10.1159/000199218. PMID 4018446.
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