Glutamine N-acyltransferase

In enzymology, a glutamine N-acyltransferase (EC 2.3.1.68) is an enzyme that catalyzes the chemical reaction

acyl-CoA + L-glutamine CoA + N-acyl-L-glutamine
glutamine N-acyltransferase
Identifiers
EC number2.3.1.68
CAS number9030-00-6
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

Thus, the two substrates of this enzyme are acyl-CoA and L-glutamine, whereas its two products are CoA and N-acyl-L-glutamine.

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is acyl-CoA:L-glutamine N-acyltransferase.

References

    • Webster LT, Siddiqui UA, Lucas SV, Strong JM, Mieyal JJ (1976). "Identification of separate acyl- CoA:glycine and acyl-CoA:L-glutamine N-acyltransferase activities in mitochondrial fractions from liver of rhesus monkey and man". J. Biol. Chem. 251 (11): 3352–8. PMID 931988.


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