Geranylgeraniol 18-hydroxylase

Geranylgeraniol 18-hydroxylase (EC 1.14.13.110, GGOH-18-hydroxylase) is an enzyme with systematic name geranylgeraniol,NADPH:oxygen oxidoreductase (18-hydroxylating).[1] This enzyme catalyses the following chemical reaction

geranylgeraniol + NADPH + H+ + O2 18-hydroxygeranylgeraniol + NADP+ + H2O
Geranylgeraniol 18-hydroxylase
Identifiers
EC number1.14.13.110
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

Geranylgeraniol 18-hydroxylase is a heme-thiolate protein (P-450).

References

  1. Tansakul P, De-Eknamkul W (1998). "Geranylgeraniol-18-hydroxylase: the last enzyme in the plaunotol biosynthetic pathway in Croton sublyratus". Phytochemistry. 47 (7): 1241–1246. doi:10.1016/s0031-9422(97)00743-7.
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