GLRX3

Glutaredoxin-3 is a protein that in humans is encoded by the GLRX3 gene.[5][6][7]

GLRX3
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesGLRX3, GLRX4, GRX3, GRX4, PICOT, TXNL2, TXNL3, glutaredoxin 3
External IDsOMIM: 612754 MGI: 1353653 HomoloGene: 4769 GeneCards: GLRX3
Gene location (Human)
Chr.Chromosome 10 (human)[1]
Band10q26.3Start130,136,391 bp[1]
End130,184,521 bp[1]
RNA expression pattern




More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

10539

30926

Ensembl

ENSG00000108010

ENSMUSG00000031068

UniProt

O76003

Q9CQM9

RefSeq (mRNA)

NM_001199868
NM_006541
NM_001321980

NM_023140
NM_001348093

RefSeq (protein)

NP_001186797
NP_001308909
NP_006532

NP_075629
NP_001335022

Location (UCSC)Chr 10: 130.14 – 130.18 MbChr 7: 137.44 – 137.47 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Interactions

GLRX3 has been shown to interact with PRKCQ.[5]

References

  1. GRCh38: Ensembl release 89: ENSG00000108010 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000031068 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Witte S, Villalba M, Bi K, Liu Y, Isakov N, Altman A (Feb 2000). "Inhibition of the c-Jun N-terminal kinase/AP-1 and NF-kappaB pathways by PICOT, a novel protein kinase C-interacting protein with a thioredoxin homology domain". J Biol Chem. 275 (3): 1902–9. doi:10.1074/jbc.275.3.1902. PMID 10636891.
  6. Stanchi F, Bertocco E, Toppo S, Dioguardi R, Simionati B, Cannata N, Zimbello R, Lanfranchi G, Valle G (Jan 2001). "Characterization of 16 novel human genes showing high similarity to yeast sequences". Yeast. 18 (1): 69–80. doi:10.1002/1097-0061(200101)18:1<69::AID-YEA647>3.0.CO;2-H. PMID 11124703.
  7. "Entrez Gene: TXNL2 thioredoxin-like 2".

Further reading

  • Overview of all the structural information available in the PDB for UniProt: O76003 (Human Glutaredoxin-3 (GLRX3)) at the PDBe-KB.



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