Fumigaclavine B O-acetyltransferase

Fumigaclavine B O-acetyltransferase (EC 2.3.1.205, FgaAT) is an enzyme with systematic name acetyl-CoA:fumigaclavine B O-acetyltransferase.[1] This enzyme catalyses the following chemical reaction

acetyl-CoA + fumigaclavine B CoA + fumigaclavine A
Fumigaclavine B O-acetyltransferase
Identifiers
EC number2.3.1.205
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

The enzyme participates in the biosynthesis of fumigaclavine C, an ergot alkaloid.

References

  1. Liu X, Wang L, Steffan N, Yin WB, Li SM (September 2009). "Ergot alkaloid biosynthesis in Aspergillus fumigatus: FgaAT catalyses the acetylation of fumigaclavine B". ChemBioChem. 10 (14): 2325–8. doi:10.1002/cbic.200900395. PMID 19672909.
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