Formate dehydrogenase (cytochrome-c-553)

In enzymology, a formate dehydrogenase (cytochrome-c-553) (EC 1.2.2.3) is an enzyme that catalyzes the chemical reaction

formate + ferricytochrome c-553 CO2 + ferrocytochrome c-553
formate dehydrogenase (cytochrome-c-553)
Identifiers
EC number1.2.2.3
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

Thus, the two substrates of this enzyme are formate and ferricytochrome c-553, whereas its two products are CO2 and ferrocytochrome c-553.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with a cytochrome as acceptor. The systematic name of this enzyme class is formate:ferricytochrome-c-553 oxidoreductase.

References

    • Yagi T (October 1969). "Formate: cytochrome oxidoreductase of Desulfovibrio vulgaris". Journal of Biochemistry. 66 (4): 473–8. doi:10.1093/oxfordjournals.jbchem.a129171. PMID 4982127.
    • Yagi T (October 1979). "Purification and properties of cytochrome c-553, an electron acceptor for formate dehydrogenase of Desulfovibrio vulgaris, Miyazaki". Biochimica et Biophysica Acta (BBA) - Bioenergetics. 548 (1): 96–105. doi:10.1016/0005-2728(79)90190-7. PMID 226135.


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