Ecdysone oxidase

In enzymology, an ecdysone oxidase (EC 1.1.3.16) is an enzyme that catalyzes the chemical reaction

ecdysone + O2 3-dehydroecdysone + H2O2
ecdysone oxidase
Identifiers
EC number1.1.3.16
CAS number56803-12-4
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

Thus, the two substrates of this enzyme are ecdysone and O2, whereas its two products are 3-dehydroecdysone and H2O2.

This enzyme may or may not belong to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with oxygen as acceptor. The systematic name of this enzyme class is ecdysone:oxygen 3-oxidoreductase. This enzyme might also called beta-ecdysone oxidase.

References

    • Koolman J, Karlson P (1975). "Ecdysone Oxidase, an enzyme from the blowfly Calliphora erythrocephala (Meigen)". Hoppe-Seyler's Z. Physiol. Chem. 356 (7): 1131–8. doi:10.1515/bchm2.1975.356.2.1131. PMID 297.


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