dTDP-L-rhamnose 4-epimerase

DTDP-L-rhamnose 4-epimerase (EC 5.1.3.25, dTDP-4-L-rhamnose 4-epimerase, wbiB (gene)) is an enzyme with systematic name dTDP-6-deoxy-beta-L-talose 4-epimerase.[1] This enzyme catalyses the following chemical reaction

dTDP-6-deoxy-beta-L-talose dTDP-6-deoxy-beta-L-mannose

DTDP-L-rhamnose 4-epimerase
Identifiers
EC number5.1.3.25
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

The equilibrium is strongly towards dTDP-6-deoxy-beta-L-mannose.

References

  1. Yoo HG, Kwon SY, Karki S, Kwon HJ (July 2011). "A new route to dTDP-6-deoxy-l-talose and dTDP-L-rhamnose: dTDP-L-rhamnose 4-epimerase in Burkholderia thailandensis". Bioorganic & Medicinal Chemistry Letters. 21 (13): 3914–7. doi:10.1016/j.bmcl.2011.05.030. PMID 21640586.
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