D-arabitol-phosphate dehydrogenase

D-arabitol-phosphate dehydrogenase (EC 1.1.1.301, APDH, D-arabitol 1-phosphate dehydrogenase, D-arabitol 5-phosphate dehydrogenase) is an enzyme with systematic name D-arabitol-phosphate:NAD+ oxidoreductase.[1] This enzyme catalyses the following chemical reaction

D-arabitol 1-phosphate + NAD+ D-xylulose 5-phosphate + NADH + H+
D-arabitol-phosphate dehydrogenase
Identifiers
EC number1.1.1.301
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

This enzyme participates in arabitol catabolism. The enzyme also converts D-arabitol 5-phosphate to D-ribulose 5-phosphate at a lower rate.

References

  1. Povelainen M, Eneyskaya EV, Kulminskaya AA, Ivanen DR, Kalkkinen N, Neustroev KN, Miasnikov AN (April 2003). "Biochemical and genetic characterization of a novel enzyme of pentitol metabolism: D-arabitol-phosphate dehydrogenase". The Biochemical Journal. 371 (Pt 1): 191–7. doi:10.1042/BJ20021096. PMC 1223252. PMID 12467497.


This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.