Cucurbitadienol synthase

Cucurbitadienol synthase (EC 5.4.99.33, CPQ (gene), (S)-2,3-epoxysqualene mutase (cyclizing, cucurbitadienol-forming)) is an enzyme with systematic name (3S)-2,3-epoxy-2,3-dihydrosqualene mutase (cyclizing, cucurbitadienol-forming).[1] This enzyme catalyses the following chemical reaction

(3S)-2,3-epoxysqualene cucurbitadienol
Cucurbitadienol synthase
Identifiers
EC number5.4.99.33
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

References

  1. Shibuya M, Adachi S, Ebizuka Y (2004). "Cucurbitadienol synthase, the first committed enzyme for cucurbitacin biosynthesis, is a distinct enzyme from cycloartenol synthase for phytosterol biosynthesis". Tetrahedron. 60: 6995–7003. doi:10.1016/j.tet.2004.04.088.
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