Chlorophyll synthase
In enzymology, chlorophyll synthase (EC 2.5.1.62) is an enzyme that catalyzes the chemical reaction
- chlorophyllide a + phytyl diphosphate chlorophyll a + diphosphate
| chlorophyll synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.5.1.62 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
The two substrates of this enzyme are chlorophyllide a and phytyl diphosphate; its two products are chlorophyll a and diphosphate. The same enzyme can act on chlorophyllide b to form chlorophyll b.
- Structures of the main substrate and product of the enzyme
Chlorophyllide a
Chlorophyll a
This enzyme belongs to the family of transferases, specifically those transferring aryl or alkyl groups other than methyl groups. The systematic name of this enzyme class is chlorophyllide-a:phytyl-diphosphate phytyltransferase. This reaction is the final step of the complete biosynthetic pathway to chlorophylls from glutamic acid.[1][2]
See also
References
- Willows, Robert D. (2003). "Biosynthesis of chlorophylls from protoporphyrin IX". Natural Product Reports. 20 (6): 327–341. doi:10.1039/B110549N. PMID 12828371.
- Bollivar, David W. (2007). "Recent advances in chlorophyll biosynthesis". Photosynthesis Research. 90 (2): 173–194. doi:10.1007/s11120-006-9076-6. PMID 17370354.
- Schmid HC, Rassadina V, Oster U, Schoch S, Rudiger W (2002). "Pre-loading of chlorophyll synthase with tetraprenyl diphosphate is an obligatory step in chlorophyll biosynthesis" (PDF). Biol. Chem. 383 (11): 1769–78. doi:10.1515/BC.2002.198. PMID 12530542.
- Oster U, Bauer CE, Rudiger W (1997). "Characterization of chlorophyll a and bacteriochlorophyll a synthases by heterologous expression in Escherichia coli". J. Biol. Chem. 272 (15): 9671–6. doi:10.1074/jbc.272.15.9671. PMID 9092496.
- Rudiger W, Benz J, Guthoff C (1980). "Detection and partial characterization of activity of chlorophyll synthetase in etioplast membranes". Eur. J. Biochem. 109 (1): 193–200. doi:10.1111/j.1432-1033.1980.tb04784.x. PMID 7408876.
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