CSF/serum glucose ratio

The CSF/serum glucose ratio, also known as CSF/Blood glucose ratio, is a measurement used to compare CSF glucose and blood sugar.

CSF/serum glucose ratio
Reference range0.6
LOINC2352-3

Because many bacteria metabolize glucose, and because the blood brain barrier minimizes transversal, the ratio can be useful in determining whether there is a bacterial infection in the CSF.

The normal ratio is 0.6.[1]

It is used to distinguish between bacterial and viral meningitis, as it is often lowered in bacterial meningitis and normal in viral meningitis.[2]

References

Pathophysiology sample values
BMP/ELECTROLYTES:
Na+ = 140 Cl = 100 BUN = 20 /
Glu = 150
K+ = 4 CO2 = 22 PCr = 1.0 \
ARTERIAL BLOOD GAS:
HCO3 = 24 paCO2 = 40 paO2 = 95 pH = 7.40
ALVEOLAR GAS:
pACO2 = 36 pAO2 = 105 A-a g = 10
OTHER:
Ca = 9.5 Mg2+ = 2.0 PO4 = 1
CK = 55 BE = −0.36 AG = 16
SERUM OSMOLARITY/RENAL:
PMO = 300 PCO = 295 POG = 5 BUN:Cr = 20
URINALYSIS:
UNa+ = 80 UCl = 100 UAG = 5 FENa = 0.95
UK+ = 25 USG = 1.01 UCr = 60 UO = 800
PROTEIN/GI/LIVER FUNCTION TESTS:
LDH = 100 TP = 7.6 AST = 25 TBIL = 0.7
ALP = 71 Alb = 4.0 ALT = 40 BC = 0.5
AST/ALT = 0.6 BU = 0.2
AF alb = 3.0 SAAG = 1.0 SOG = 60
CSF:
CSF alb = 30 CSF glu = 60 CSF/S alb = 7.5 CSF/S glu = 0.4
  1. Karen Roos (2005). Principles of neurologic infectious diseases. New York: McGraw-Hill, Medical Pub. Division. p. 4. ISBN 0-07-140816-9.
  2. Tamune H; et al. (2014). "Cerebrospinal fluid/blood glucose ratio as an indicator for bacterial meningitis". Am J Emerg Med. 32 (3): 263–6. doi:10.1016/j.ajem.2013.11.030. PMID 24361137.


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