CALN1
Calcium-binding protein 8 is a protein that in humans is encoded by the CALN1 gene.[5][6] Alternative splicing results in multiple transcript variants.[6]
| CALN1 | |||||||||||||||||||||||||
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| Identifiers | |||||||||||||||||||||||||
| Aliases | CALN1, CABP8, calneuron 1 | ||||||||||||||||||||||||
| External IDs | OMIM: 607176 MGI: 2155987 HomoloGene: 10966 GeneCards: CALN1 | ||||||||||||||||||||||||
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| Species | Human | Mouse | |||||||||||||||||||||||
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| Location (UCSC) | Chr 7: 71.78 – 72.45 Mb | Chr 5: 130.37 – 130.85 Mb | |||||||||||||||||||||||
| PubMed search | [3] | [4] | |||||||||||||||||||||||
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Function
This gene encodes a protein with high similarity to the calcium-binding proteins of the calmodulin family. The encoded protein contains two EF-hand domains and potential calcium-binding sites.[7]
References
- GRCh38: Ensembl release 89: ENSG00000183166 - Ensembl, May 2017
- GRCm38: Ensembl release 89: ENSMUSG00000060371 - Ensembl, May 2017
- "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- Wu YQ, Lin X, Liu CM, Jamrich M, Shaffer LG (Apr 2001). "Identification of a human brain-specific gene, calneuron 1, a new member of the calmodulin superfamily". Molecular Genetics and Metabolism. 72 (4): 343–50. doi:10.1006/mgme.2001.3160. PMID 11286509.
- "Entrez Gene: CALN1 calneuron 1".
- McCue HV, Haynes LP, Burgoyne RD (Aug 2010). "The diversity of calcium sensor proteins in the regulation of neuronal function". Cold Spring Harbor Perspectives in Biology. 2 (8): a004085. doi:10.1101/cshperspect.a004085. PMC 2908765. PMID 20668007.
External links
- Human CALN1 genome location and CALN1 gene details page in the UCSC Genome Browser.
Further reading
- Andersson B, Wentland MA, Ricafrente JY, Liu W, Gibbs RA (Apr 1996). "A "double adaptor" method for improved shotgun library construction". Analytical Biochemistry. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.
- Yu W, Andersson B, Worley KC, Muzny DM, Ding Y, Liu W, Ricafrente JY, Wentland MA, Lennon G, Gibbs RA (Apr 1997). "Large-scale concatenation cDNA sequencing". Genome Research. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC 139146. PMID 9110174.
- "Toward a complete human genome sequence". Genome Research. 8 (11): 1097–108. Nov 1998. doi:10.1101/gr.8.11.1097. PMID 9847074.
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