Butanal dehydrogenase
In enzymology, a butanal dehydrogenase (EC 1.2.1.57) is an enzyme that catalyzes the chemical reaction
- butanal + CoA + NAD(P)+ butanoyl-CoA + NAD(P)H + H+
| butanal dehydrogenase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 1.2.1.57 | ||||||||
| CAS number | 116412-25-0 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
The 4 substrates of this enzyme are butanal, CoA, NAD+, and NADP+, whereas its 4 products are butanoyl-CoA, NADH, NADPH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is butanal:NAD(P)+ oxidoreductase (CoA-acylating). This enzyme participates in butanoate metabolism.
References
- Palosaari NR, Rogers P (1988). "Purification and properties of the inducible coenzyme A-linked butyraldehyde dehydrogenase from Clostridium acetobutylicum". J. Bacteriol. 170 (7): 2971–6. PMC 211236. PMID 3384801.
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