Benzil reductase ((R)-benzoin forming)

Benzil reductase ((R)-benzoin forming) (EC 1.1.1.321) is an enzyme with systematic name (R)-benzoin:NADP+ oxidoreductase.[1] This enzyme catalyses the following chemical reaction

(R)-benzoin + NADP+ benzil + NADPH + H+
Benzil reductase ((R)-benzoin forming)
Identifiers
EC number1.1.1.321
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

The bacterial enzyme (Xanthomonas oryzae) enantioselectively reduces one of the two carbonyl groups of benzil to form optically active (R)-benzoin.

References

  1. Konishi J, Ohta H, Tuchihashi G (1985). "Asymmetric reduction of benzil to benzoin catalyzed by the enzyme system of a microorganism". Chem. Lett. 14: 1111–1112. doi:10.1246/cl.1985.1111.
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