Aviv Regev

Aviv Regev is a computational biologist at the Broad Institute of MIT and Harvard, Professor at the Department of Biology at Massachusetts Institute of Technology[3] and Investigator at the Howard Hughes Medical Institute.[4] Effective August 1, 2020, she is slated to become head of Genentech research and early development.

Aviv Regev
Aviv Regev at the Intelligent Systems for Molecular Biology conference in 2017
Born(1971-07-11)July 11, 1971
Alma materTel Aviv University, Adi Lautman Interdisciplinary Programme for Outstanding Students
Awards
Scientific career
FieldsBioinformatics
Computational Biology
Institutions
Doctoral advisorEva Jablonka
Ehud Shapiro
Websitebroadinstitute.org/bios/aviv-regev

Education

Regev studied at the Adi Lautman Interdisciplinary Programme for Outstanding Students of Tel Aviv University, where she completed her Ph.D. under the supervision of Eva Jablonka[5] and Ehud Shapiro.[6]

Career

Regev served as the Core Institute Member, Chair of the Faculty, and Co-director of the Cell Circuits Program at the Broad Institute. On May 11, 2020, Roche announced that Dr. Regev will be the Head of Genentech Research and Early Development (gRED) and become a member of the enlarged Corporate Executive Committee on August 1, 2020. She will be based in South San Francisco.[7][8]

Research

Regev's highly cited[9][10] research includes work on gene expression[11][12] (with Eran Segal and David Botstein), and the use of π-calculus to represent biochemical processes.[13][14][15] Regev’s team has been a leading pioneer of single-cell genomics experimental and computational methods.[16]

Awards and honors

Regev was awarded the Overton Prize in 2008 for "outstanding accomplishment to a scientist in the early to mid stage of his or her career".[1] She was awarded the ISCB Innovator Award in 2017.[2][17] In 2008, she was also awarded the NIH Director's Pioneer Award[18]. She has also been awarded the Burroughs Wellcome Fund Career Award.[19] In 2017, she was awarded a Paul Marks Prize for Cancer Research.[20]

She was elected to the National Academy of Sciences in 2019.[21]

References
  1. Sansom, C.; Morrison Mckay, B. J. (2008). Bourne, Philip E. (ed.). "ISCB Honors David Haussler and Aviv Regev". PLOS Computational Biology. 4 (7): e1000101. doi:10.1371/journal.pcbi.1000101. PMC 2536508. PMID 18795145.
  2. Fogg, Christiana N.; Kovats, Diane E.; Berger, Bonnie (2017). "2017 ISCB Innovator Award: Aviv Regev". PLOS Computational Biology. 13 (6): e1005558. doi:10.1371/journal.pcbi.1005558. ISSN 1553-7358. PMC 5493285. PMID 28665936.
  3. "Aviv Regev at MIT". biology.mit.edu.
  4. "Aviv Regev, PhD: Investigator / 2014–Present". hhmi.org. Howard Hughes Medical Institute.
  5. Regev, A.; Lamb, M. J.; Jablonka, E. (1998). "The Role of DNA Methylation in Invertebrates: Developmental Regulation or Genome Defense?". Molecular Biology and Evolution. 15 (7): 880. doi:10.1093/oxfordjournals.molbev.a025992. ISSN 0737-4038.
  6. Regev, A.; Shapiro, E. (2002). "Cellular abstractions: Cells as computation". Nature. 419 (6905): 343. doi:10.1038/419343a. PMC 3842595. PMID 12353013.
  7. Taylor, Nick Paul (May 11, 2020). "Genentech lures Regev from Broad Institute to lead research and early development". FierceBiotech. Retrieved 25 May 2020.
  8. "Changes to the Roche Enlarged Corporate Executive Committee" (Press release). Basel, Switzerland: F. Hoffmann-La Roche Ltd. globenewswire. May 11, 2020. Retrieved 2020-05-25.
  9. "Aviv Regev publications in Google Scholar". scholar.google.com.
  10. Search Results for author Regev A on PubMed.
  11. Segal, E.; Shapira, M.; Regev, A.; Pe'er, D.; Botstein, D.; Koller, D.; Friedman, N. (2003). "Module networks: Identifying regulatory modules and their condition-specific regulators from gene expression data". Nature Genetics. 34 (2): 166–176. doi:10.1038/ng1165. PMID 12740579.
  12. Segal, E.; Friedman, N.; Koller, D.; Regev, A. (2004). "A module map showing conditional activity of expression modules in cancer". Nature Genetics. 36 (10): 1090–1098. doi:10.1038/ng1434. PMID 15448693.
  13. Regev, A.; Silverman, W.; Shapiro, E. (2001). "Representation and simulation of biochemical processes using the pi-calculus process algebra". Pacific Symposium on Biocomputing: 459–470. doi:10.1142/9789814447362_0045. ISBN 978-981-02-4515-3. PMID 11262964.
  14. Priami, C.; et al. (2001). "Application of a stochastic name-passing calculus to representation and simulation of molecular processes" (PDF). Information Processing Letters. 80: 25–31. doi:10.1016/S0020-0190(01)00214-9.
  15. Study provides insight into regenerative potential of prostate gland, News Medical, accessed May 4, 2020.
  16. "Aviv Regev". HHMI.org. Retrieved 2020-05-11.
  17. "February 09, 2017: ISCB Announces 2017 Award Recipients". www.iscb.org. Retrieved 10 February 2017.
  18. 2008 NIH Director’s Pioneer Award
  19. Dynamic single-cell imaging of direct reprogramming reveals an early specifying event - Nature Biotechnology: Aviv Regev, Ph.D. - Career Awards at the Scientific Interface; Ab initio reconstruction of cell type–specific transcriptomes in mouse reveals the conserved multi-exonic structure of lincRNAs - Nature Biotechnology: Aviv Regev, Ph.D. - Career Awards at the Scientific Interface.
  20. "2017 Prize Winners". Memorial Sloan Kettering Cancer Center. Retrieved 12 December 2017.
  21. "2019 NAS Election". www.nasonline.org. Retrieved 30 April 2019.
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.