Aminoadipate-semialdehyde dehydrogenase
Aminoadipate-semialdehyde dehydrogenase is a protein that in humans is encoded by the AASDH gene. [5]
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| Aliases | AASDH, ACSF4, LYS2, NRPS1098, NRPS998, aminoadipate-semialdehyde dehydrogenase | ||||||||||||||||||||||||
| External IDs | OMIM: 614365 MGI: 2442517 HomoloGene: 71711 GeneCards: AASDH | ||||||||||||||||||||||||
| EC number | 1.2.1.31 | ||||||||||||||||||||||||
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| Species | Human | Mouse | |||||||||||||||||||||||
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| Location (UCSC) | Chr 4: 56.34 – 56.39 Mb | Chr 5: 76.87 – 76.91 Mb | |||||||||||||||||||||||
| PubMed search | [3] | [4] | |||||||||||||||||||||||
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Function
This gene encodes a member of the non-ribosome peptide syntesase (NRPS) enzyme family. The encoded protein contains an AMP-binding domain, PP-binding (phosphopantetheine, or pantetheine 4'phosphate-binding) domain and the Pyrrolo-quinoline quinon (PQQ) binding domain. The protein is expressed in several adult tissues.
References
- GRCh38: Ensembl release 89: ENSG00000157426 - Ensembl, May 2017
- GRCm38: Ensembl release 89: ENSMUSG00000055923 - Ensembl, May 2017
- "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- "Entrez Gene: Aminoadipate-semialdehyde dehydrogenase". Retrieved 2017-01-02.
Further reading
- Wang L, Jil C, Xu Y, Xu J, Dai J, Wu Q, Wu M, Zou X, Sun L, Gu S, Xie Y, Mao Y (2005). "Cloning and characterization of a novel human homolog* of mouse U26, a putative PQQ-dependent AAS dehydrogenase". Mol. Biol. Rep. 32 (1): 47–53. doi:10.1007/s11033-003-2716-4. PMID 15865210.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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