Alanylphosphatidylglycerol synthase
In enzymology, an alanylphosphatidylglycerol synthase (EC 2.3.2.11) is an enzyme that catalyzes the chemical reaction
- L-alanyl-tRNA + phosphatidylglycerol tRNA + 3-O-L-alanyl-1-O-phosphatidylglycerol
| alanylphosphatidylglycerol synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.3.2.11 | ||||||||
| CAS number | 37257-27-5 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Thus, the two substrates of this enzyme are L-alanyl-tRNA and phosphatidylglycerol, whereas its two products are tRNA and 3-O-L-alanyl-1-O-phosphatidylglycerol.
This enzyme belongs to the family of transferases, specifically the aminoacyltransferases. The systematic name of this enzyme class is L-alanyl-tRNA:phosphatidylglycerol alanyltransferase. Other names in common use include O-alanylphosphatidylglycerol synthase, and alanyl phosphatidylglycerol synthetase.
References
- Gould RM, Thornton MP, Liepkalns V, Lennarz WJ (1968). "Participation of aminoacyl transfer ribonucleic acid in aminoacyl phosphatidylglycerol synthesis. II. Specificity of alanyl phosphatidylglycerol synthetase". J. Biol. Chem. 243 (11): 3096–104. PMID 4297471.
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