Acetyl-CoA C-myristoyltransferase
In enzymology, an acetyl-CoA C-myristoyltransferase (EC 2.3.1.155) is an enzyme that catalyzes the chemical reaction
- myristoyl-CoA + acetyl-CoA 3-oxopalmitoyl-CoA + CoA
| acetyl-CoA C-myristoyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.3.1.155 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
| Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| Symbol | NMT_C | ||||||||
| Pfam | PF02799 | ||||||||
| InterPro | IPR022677 | ||||||||
| |||||||||
Thus, the two substrates of this enzyme are myristoyl-CoA and acetyl-CoA, whereas its two products are 3-oxopalmitoyl-CoA and CoA.
This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is myristoyl-CoA:acetyl-CoA C-myristoyltransferase.
References
- Miyazawa S, Furuta S, Osumi T, Hashimoto T, Ui N (August 1981). "Properties of peroxisomal 3-ketoacyl-coA thiolase from rat liver". J. Biochem. Tokyo. 90 (2): 511–9. PMID 6117552.
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