3-oxoadipate CoA-transferase
In enzymology, a 3-oxoadipate CoA-transferase (EC 2.8.3.6) is an enzyme that catalyzes the chemical reaction
- succinyl-CoA + 3-oxoadipate succinate + 3-oxoadipyl-CoA
| 3-oxoadipate CoA-transferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.8.3.6 | ||||||||
| CAS number | 9026-16-8 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Thus, the two substrates of this enzyme are succinyl-CoA and 3-oxoadipate, whereas its two products are succinate and 3-oxoadipyl-CoA.
This enzyme belongs to the family of transferases, specifically the CoA-transferases. The systematic name of this enzyme class is succinyl-CoA:3-oxoadipate CoA-transferase. Other names in common use include 3-oxoadipate coenzyme A-transferase, and 3-oxoadipate succinyl-CoA transferase. This enzyme participates in benzoate degradation via hydroxylation.
References
- KATAGIRI M, HAYAISHI O (1957). "Enzymatic degradation of beta-ketoadipic acid". J. Biol. Chem. 226 (1): 439–48. PMID 13428776.
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