3-hydroxybenzoate—CoA ligase

3-hydroxybenzoate—CoA ligase (EC 6.2.1.37, 3-hydroxybenzoyl-CoA synthetase, 3-hydroxybenzoate-coenzyme A ligase (AMP-forming), 3-hydroxybenzoyl coenzyme A synthetase, 3-hydroxybenzoyl-CoA ligase) is an enzyme with systematic name 3-hydroxybenzoate:CoA ligase (AMP-forming).[1] This enzyme catalyses the following chemical reaction

ATP + 3-hydroxybenzoate + CoA AMP + diphosphate + 3-hydroxybenzoyl-CoA
3-hydroxybenzoate—CoA ligase
Identifiers
EC number6.2.1.37
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

The enzyme works equally well with 4-hydroxybenzoate.

References

  1. Laempe D, Jahn M, Breese K, Schägger H, Fuchs G (February 2001). "Anaerobic metabolism of 3-hydroxybenzoate by the denitrifying bacterium Thauera aromatica". Journal of Bacteriology. 183 (3): 968–79. doi:10.1128/jb.183.3.968-979.2001. PMC 94965. PMID 11208796.
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.