2-Bromothiophene
2-Bromothiophene is an organosulfur compound with the formula C4H3BrS. It is a colorless liquid. Unlike 3-bromothiophene, the 2-bromo isomer is prepared directly by partial bromination of thiophene. It is a precursor to several drugs, including tipepidine, ticlopidine, and clopidogrel.[1]
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| Names | |
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| Preferred IUPAC name
2-Bromothiophene | |
| Other names
2-Thienyl bromide, 2BT | |
| Identifiers | |
3D model (JSmol) |
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| ChemSpider | |
| ECHA InfoCard | 100.012.454 |
| EC Number |
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PubChem CID |
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CompTox Dashboard (EPA) |
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| Properties | |
| C4H3BrS | |
| Molar mass | 163.03 g·mol−1 |
| Appearance | Colorless liquid |
| Density | 1.684 g/mL |
| Melting point | −10 °C (14 °F; 263 K) |
| Boiling point | 153.5 °C (308.3 °F; 426.6 K) |
| Immiscible | |
| Hazards | |
| Main hazards | N,Xi,Xn,T |
| GHS pictograms |     |
| GHS Signal word | Danger |
GHS hazard statements |
H226, H300, H301, H310, H315, H318, H319, H330 |
| P210, P233, P240, P241, P242, P243, P260, P262, P264, P270, P271, P280, P284, P301+310, P302+350, P302+352, P303+361+353, P304+340, P305+351+338, P310, P320, P321, P322, P330, P332+313 | |
| Flash point | 56 °C (133 °F; 329 K) |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
| Infobox references | |
References
- Jonathan Swanston (2006). "Thiophene". Ullmann's Encyclopedia of Industrial Chemistry. Weinheim: Wiley-VCH. doi:10.1002/14356007.a26_793.pub2.
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