16S rRNA (uracil1498-N3)-methyltransferase
16S rRNA (uracil1498-N3)-methyltransferase (EC 2.1.1.193, DUF558 protein, YggJ, RsmE, m3U1498 specific methyltransferase) is an enzyme with systematic name S-adenosyl-L-methionine:16S rRNA (uracil1498-N3)-methyltransferase.[1][2] This enzyme catalyses the following chemical reaction
- S-adenosyl-L-methionine + uracil1498 in 16S rRNA S-adenosyl-L-homocysteine + N3-methyluracil1498 in 16S rRNA
| 16S rRNA (uracil1498-N3)-methyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.1.1.193 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
The enzyme specifically methylates uracil1498 at N3 in 16S rRNA.
References
- Basturea GN, Rudd KE, Deutscher MP (March 2006). "Identification and characterization of RsmE, the founding member of a new RNA base methyltransferase family". RNA. 12 (3): 426–34. doi:10.1261/rna.2283106. PMC 1383581. PMID 16431987.
- Basturea GN, Deutscher MP (November 2007). "Substrate specificity and properties of the Escherichia coli 16S rRNA methyltransferase, RsmE". RNA. 13 (11): 1969–76. doi:10.1261/rna.700507. PMC 2040091. PMID 17872509.
External links
- 16S+rRNA+(uracil1498-N3)-methyltransferase at the US National Library of Medicine Medical Subject Headings (MeSH)
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