10-deacetylbaccatin III 10-O-acetyltransferase
In enzymology, a 10-deacetylbaccatin III 10-O-acetyltransferase (EC 2.3.1.167) is an enzyme that catalyzes the chemical reaction
- acetyl-CoA + 10-deacetylbaccatin III CoA + baccatin III
| 10-deacetylbaccatin III 10-O-acetyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.3.1.167 | ||||||||
| CAS number | 220946-63-4 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Thus, the two substrates of this enzyme are acetyl-CoA and 10-deacetylbaccatin III, whereas its two products are CoA and baccatin III.
This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is acetyl-CoA:taxan-10beta-ol O-acetyltransferase. This enzyme participates in diterpenoid biosynthesis.
References
- Walker K, Croteau R (2000). "Molecular cloning of a 10-deacetylbaccatin III-10-O-acetyl transferase cDNA from Taxus and functional expression in Escherichia coli". Proc. Natl. Acad. Sci. U.S.A. 97 (2): 583–7. doi:10.1073/pnas.97.2.583. PMC 15373. PMID 10639122.
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