1-alkenylglycerophosphoethanolamine O-acyltransferase
In enzymology, a 1-alkenylglycerophosphoethanolamine O-acyltransferase (EC 2.3.1.121) is an enzyme that catalyzes the chemical reaction
- acyl-CoA + 1-alkenylglycerophosphoethanolamine CoA + 1-alkenyl-2-acylglycerophosphoethanolamine
| 1-alkenylglycerophosphoethanolamine O-acyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.3.1.121 | ||||||||
| CAS number | 112445-17-7 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Thus, the two substrates of this enzyme are acyl-CoA and 1-alkenylglycerophosphoethanolamine, whereas its two products are CoA and 1-alkenyl-2-acylglycerophosphoethanolamine.
This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is acyl-CoA:1-alkenylglycerophosphoethanolamine O-acyltransferase. This enzyme participates in ether lipid metabolism.
References
- Arthur G, Page L, Choy PC (1987). "Acylation of 1-alkenylglycerophosphoethanolamine and 1-acylglycerophosphoethanolamine in guinea-pig heart microsomes". Biochim. Biophys. Acta. 921 (2): 259–65. doi:10.1016/0005-2760(87)90026-9. PMID 3651487.
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