1-Deoxy-11beta-hydroxypentalenate dehydrogenase
1-deoxy-11beta-hydroxypentalenate dehydrogenase (EC 1.1.1.340, 1-deoxy-11beta-hydroxypentalenic acid dehydrogenase, ptlF (gene), penF (gene name)) is an enzyme with systematic name 1-deoxy-11beta-hydroxypentalenate:NAD+ oxidoreductase.[1] This enzyme catalyses the following chemical reaction
- 1-deoxy-11beta-hydroxypentalenate + NAD+ 1-deoxy-11-oxopentalenate + NADH + H+
| 1-deoxy-11beta-hydroxypentalenate dehydrogenase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 1.1.1.340 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
This enzyme from the bacterium Streptomyces avermitilis participates in pentalenolactone biosynthesis.
References
- You Z, Omura S, Ikeda H, Cane DE (March 2007). "Pentalenolactone biosynthesis: Molecular cloning and assignment of biochemical function to PtlF, a short-chain dehydrogenase from Streptomyces avermitilis, and identification of a new biosynthetic intermediate". Archives of Biochemistry and Biophysics. 459 (2): 233–40. doi:10.1016/j.abb.2006.11.016. PMC 1857356. PMID 17178094.
External links
- 1-deoxy-11beta-hydroxypentalenate+dehydrogenase at the US National Library of Medicine Medical Subject Headings (MeSH)
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