(myelin-proteolipid) O-palmitoyltransferase
In enzymology, a [myelin-proteolipid] O-palmitoyltransferase (EC 2.3.1.100) is an enzyme that catalyzes the chemical reaction
- palmitoyl-CoA + [myelin proteolipid] CoA + O-palmitoyl-[myelin proteolipid]
| myelin-proteolipid O-palmitoyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.3.1.100 | ||||||||
| CAS number | 82657-98-5 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Thus, the two substrates of this enzyme are palmitoyl-CoA and myelin proteolipid, whereas its two products are CoA and O-palmitoyl-myelin proteolipid.
This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is palmitoyl-CoA:[myelin-proteolipid] O-palmitoyltransferase. Other names in common use include myelin PLP acyltransferase, acyl-protein synthetase, and myelin-proteolipid O-palmitoyltransferase.
References
- Bizzozero OA, McGarry JF, Lees MB (1987). "Acylation of endogenous myelin proteolipid protein with different acyl-CoAs". J. Biol. Chem. 262 (5): 2138–45. PMID 3818589.
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