(+)-neomenthol dehydrogenase
In enzymology, a (+)-neomenthol dehydrogenase (EC 1.1.1.208) is an enzyme that catalyzes the chemical reaction
- (+)-neomenthol + NADP+ (−)-menthone + NADPH + H+
| (+)-neomenthol dehydrogenase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 1.1.1.208 | ||||||||
| CAS number | 81811-47-4 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Thus, the two substrates of this enzyme are (+)-neomenthol and NADP+, whereas its 3 products are (−)-menthone, NADPH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is (+)-neomenthol:NADP+ oxidoreductase. This enzyme is also called monoterpenoid dehydrogenase. This enzyme participates in monoterpenoid biosynthesis.
References
- Kjonaas R, Martinkus-Taylor C, Croteau R (May 1982). "Metabolism of Monoterpenes: Conversion of l-Menthone to l-Menthol and d-Neomenthol by Stereospecific Dehydrogenases from Peppermint (Mentha piperita) Leaves". Plant Physiology. 69 (5): 1013–7. doi:10.1104/pp.69.5.1013. PMC 426349. PMID 16662335.
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